Investigate the effects of early interventions for the upper paretic limb post stroke
Exploring dynamics in cerebral plasticity during upper limb recovery after stroke
Improving early prediction of outcome of the upper paretic limb after stroke
Exploring what patients exactly learn when showing functional recovery in the upper paretic limb after stroke.
To accomplish these aims the project is divided into sub-projects A1-2, B1-3, and C.
General research plan for Explicit-stroke
Explicit-stroke has been designed to include four closely inter-related phases and 3 main projects (projects A,B and C).
The two A projects and aim to investigate the effects of CIMT (A1) and EMG-NMS (A2) .
The three B projects are aimed at examining (1) the learning- and time-dependent changes in cortical neuroplasticity after MCA (middle cerebral artery) stroke (B1); (2) the kinematic changes (B2) and (3) the biomechanical changes (B3) related to upper limb recovery in the first 6 months post stroke.
Project C will investigate the longitudinal, quasi-causal relationship between, on the one hand, observed improvements in upper limb function, and, on the other hand, (a) dynamics in cortical plasticity (also B1); (b) changes in body functions and kinematics (also B2) and (c) changes in the stiffness of the paretic upper limb in the first 6 months (alsoB3).
Prof. dr. Hans Arendzen
Dr. Carel Meskers
drs. Hanneke van der Krogt
Prof. dr. Gert Kwakkel
Dr. Erwin van Wegen
drs. Joost van Kordelaar
drs. Rinske Nijland
Prof. dr. Eline Lindeman
Dr. Anne Visser
drs. Floor Buma
Prof. dr. Alexander Geurts
Dr. Annet van Kuijk
drs. Chantal Bakker
Prof. dr. Frans van der Helm
Dr. E. de Vlugt
drs. Asbjorn Klomp